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Rajesh Sharma

Doctor of Philosophy, (Veterinary Science)
Study Completed: 2010
College of Sciences

Citation

Thesis Title
The effects of uterine environment upon embryonic, fetal, neonatal and post-natal development and glucose metabolism in sheep

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Mr Sharma examined the effects of uterine environment upon embryonic, fetal, neonatal and post-natal development as well as glucose metabolism in sheep. He developed methods to collect and morphologically evaluate peri-implantation embryos and their trophoblasts. He found that a restricted uterine environment impaired embryonic, fetal, and neonatal development of lambs with the effects remaining consistent during subsequent post-natal age of up to at least one year. A luxurious uterine environment had no effect on the development of the lambs, and it improved their glucose metabolism within the first year of birth. This study is a first in showing the importance of the early embryonic period in the development of lambs and indicated significant biological and economical implications of the uterine environment in sheep production.

Supervisors
Professor Tim Parkinson
Professor Hugh Blair
Professor John Cockrem
Professor Paul Kenyon

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